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The stage is set for a intriguing Premier League matchup as league leaders Arsenal entertain struggling Wolverhampton Wanderers to the Emirates Stadium.

Confirmed Sides

Arsenal have opted for three changes following the team that endured a 2-1 defeat at Aston Villa last weekend. The French defender, the Swedish striker and Gabriel Martinelli all come into the starting eleven. Martin Ødegaard and the Spanish midfielder drop to the bench, while the Italian defender is absent. Saliba returns after missing a run of games through injury.

The visitors also have made three adjustments to their lineup after being heavily defeated 4-1 at home by Manchester United last time out. The experienced full-back, the Brazilian midfielder and Hwang Hee-chan come in. Ki-Jana Hoever and Arias drop to the bench, while Jean‐Ricner Bellegarde is not in the squad altogether.

Confirmed Lineups

Arsenal: Raya, White, Saliba, Hincapie, Timber, Eze, Zubimendi, Rice, Saka, Gyokeres, Martinelli.
Bench: Arrizabalaga, Odegaard, Gabriel Jesus, Norgaard, Trossard, Madueke, Nwaneri, Merino, Lewis-Skelly.

Wolverhampton Wanderers: Johnstone, Mosquera, Agbadou, Toti Gomes, Doherty, Joao Gomes, Andre Trindade, Krejci, Wolfe, Larsen, Hwang.
Substitutes: Tchatchoua, Mane, Lopez, Hoever, Chirewa, Arokodare, Arias, Santiago Bueno, Jose Sa.

Referee: Robert Jones
Video Assistant Referee: John Brooks

The Setup

Welcome! Because, c’mon …

The standings reveals a striking picture. Arsenal sit proudly at the summit of the Premier League, while Wolves occupy the bottom of the league.

… yet while this will be the 42nd time the Premier League leaders have faced the team at the foot of the entire table – with 30 out of 41, with seven draws – which team is behind two of the four all-time upsets? Why, Wolverhampton Wanderers, that’s who! So while the Arsenal manager will undoubtedly be anticipating another victory, Rob Edwards must know that underdogs sometimes find the target, and you never know. Kick-off is at 8pm GMT. The action is imminent!

^{(The remaining bottom-beats-top victories in the Premier League era are Oldham Athletic's 1-0 win over United in March 1993, and Spurs – admittedly, this one sounds a bit weird - defeating Liverpool in November 2008.)}